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| 多组学分析在昆虫滞育中的应用 |
| Application of multi-omics analysis to diapause in insects |
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| DOI： |
| 中文关键词: 多组学 昆虫滞育 转录组学 蛋白质组学 代谢组学 |
| 英文关键词:Multi-omics insect diapause transcriptomics proteomics metabolomics |
| 基金项目:国家自然科学基金（81902096，81871685）；山东省医学科学院医药卫生科技创新工程 |
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| 中文摘要: |
| 组学技术将生物的相关问题分别展现在基因、蛋白质和代谢物等不同层次水平上，已成为解读生命过程的重要工具。本文分别从转录组学、蛋白质组学、代谢组学以及组学间的联合应用等方面概括总结了组学技术在昆虫滞育研究中的应用情况，阐述了以转录组学、蛋白质组学和代谢组学为代表的多组学技术在昆虫滞育调控分子机制中取得的重要成果，并针对当前研究现状，对昆虫滞育中组学技术应用的前景和局限性进行了总结和展望，以期为昆虫滞育调控分子机制的研究提供参考依据。 |
| 英文摘要: |
| Omics technology has become an important tool to interpret the life process by presenting biological related issues at different levels, such as genes, proteins and metabolites. This paper summarizes the application of omics technology in the study of insect diapause from the aspects of transcriptomics, proteomics, metabolomics and combined application of omics, and expounds the important achievements of multi-omics technology represented by transcriptomics, proteomics and metabolomics in the molecular mechanism of insect diapause regulation. In view of the current research status, the prospects and limitations of the application of multi-omics techniques in insect diapause were summarized and prospected in order to provide reference for the study of the molecular mechanism of insect diapause regulation. |
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