| Insects are the most diverse biological species on earth, and insect antimicrobial peptides also exhibited more biological activities than those produced by other organisms. Furthermore, the structure, and its effects and mechanisms were gradually elucidated with the increasing research on antibacterial peptides. Recently, they were widely used in the field of animal husbandry, food industry and medicine. However, insect antibacterial peptides were not applied to the patients till now. In order to progress the application of insect antibacterial peptides in clinical application, this manuscript reviewed the structure, the classification, its potential medical applications and the production of insect antibacterial peptides. We hope it could provide the theoretical support for the research and development of insect antibacterial peptides used for antibacterial, antiviral, antitumor and antiparasitic drugs. |